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BIG-KP

This study investigates 8 subcortical brain regions divided by the left and right hemispheres. We demonstrate the use of Highly Efficient Imaging Genetics (HEIG) to compute Voxel-level GWAS. This method preserves 85-90% of the total variance at a fraction of the storage cost.

6 different vertice shape features measured:

   F1 = Radial Distance, F2 = mTBM1, F4 = mTBM3, F5 = Determinant, F6 = Max Eigenvalue, F7 = min eigenvalue

GWAS summary statistics download here.

Take a look below to see some of our findings!


Subcortical regions

Full Brain
Click on any of the subcortical regions below to start!
Accumen

Accumen

Amygdala

Amygdala

Caudate

Caudate

Hippocampus

Hippocampus

Pallidum

Pallidum

Putamin

Putamin

Thalamus

Thalamus

Ventricle

Ventricle

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